Brand Name: ReVia (not available in generic)

Manufacturer: DuPont Pharma

Description: A pure opioid antagonist that markedly attenuates or completely blocks, reversibly, the subjective effects of intravenously administered opioids. The mechanism of action in alcoholism is not understood; however, opioid antagonists have been shown to reduce alcohol consumption in animals. ReVia has been shown to decrease the craving, change the drinking experience by giving a significantly less intoxicating effect and decrease the primary effect of the first drink.

Indications and Usage: For the treatment of alcohol dependence and for the blockade of the effects of exogenously administered opioids.

Contraindications, Warnings, and Precautions: Contraindicated in patients receiving opioid analgesics, patients currently dependent on opioids, patients in acute opioid withdrawal, individuals who have failed the Narcan challenge test or who has a positive urine screen for opioids, and individuals with acute hepatitis or liver failure. ReVia can cause hepatocellular injury when given in excessive doses. When taking ReVia, be sure to carry your medication identification card with you at all times. In an emergency situation requiring analgesia, doctors must be made aware that you take this drug. Take ReVia as prescribed by you doctor. If you self-administer heroin or any other opiate drug in small doses, you will not perceive any effect. If you attempt to self-administer large doses of heroin or any other narcotic, you may die or sustain serious injury, including coma.

Adverse Reactions: Possible common side effects include anxiety, nervousness, difficulty sleeping, abdominal discomfort, nausea and vomiting, headache and muscle or joint pain. Less common side effects include loss of appetite, diarrhea, constipation, increased thirst, increased energy, irritability, and dizziness.

Dosing Range: Recommended dosage is 50mg per day.

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© 2000 Red Oak Psychiatry Associates, P.A.    Updated 11/26/2007