 | depressed mood for most the day, nearly every day. For example, the person may report feeling "sad" or "empty". In children and adolescents, the mood can be irritable.
 | noticeable decrease in interest or pleasure in almost all or all activities most of the day, nearly every day.
 | significant weight loss or gain (a change of more than 5% of body weight in one month), or a decrease or increase in appetite nearly every day.
 | lack of sleep or increased sleeping nearly every day.
 | psychomotor agitation or retardation nearly every day (feelings or restlessness or "being slowed down")
 | feeling fatigued or having loss of energy nearly every day.
 | feelings or worthlessness or excessive or inappropriate guilt nearly every day.
 | diminished ability to think or concentrate, or indecisiveness, nearly every day.
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